International Journal of Medical Informatics
Volume 75, Issue 3 , Pages 257-267 , March 2006

Databases for knowledge discovery: Examples from biomedicine and health care

References 

  1. Van Bemmel JH, Musen MA. Handbook of Medical Informatics. Heidelberg, New York: Springer Verlag; 1997;
  2. Ng S-K, Wong M. Toward routine automatic pathway discovery from on-line scientific text abstracts. Genome Inform. 1999;10:104–112
  3. Lindsay RK, Gordon MD. Literature-based discovery by lexical statistics. J. Am. Soc. Inform. Sci. 1999;50:574–587
  4. Rindfleisch TC, Tanabe L, Weinstein JN, Hunter L. EDGAR: extraction of drugs, genes and relations from the biomedical literature. Pac. Symp. Biocomput. 2000;517–528
  5. Sekimizu T, Park HS, Tsujii J. Identifying the interaction between genes and gene products based on frequently seen verbs in MedLine abstracts. Genome Inform. Ser. Workshop Genome Inform. 1998;9:62–71
  6. Stephens M, Palakal M, Mukhopadhyay S, Raje R, Mostafa J. Detecting gene relations from MedLine abstracts. Pac. Symp. Biocomput. 2001;6:483–496
  7. Van Mulligen EM, Diwersy M, Schmidt M, Buurman H, Mons B. Facilitating networks of information. Proc. AMIA Symp. 2000;868–872
  8. Smallheiser NR, Swanson DR. Using arrowsmith: a computer-assisted approach to formulating and assessing scientific hypotheses. Comp. Methods Prog. Biomed. 1998;57:149–153
  9. Van Mulligen EM, Van der Eijk C, Kors JA, Schijvenaars RJ, Mons B. Research for research: tools for knowledge discovery and visualisation. Proc. AMIA Symp. 2002;835–839
  10. Lindberg DAB, Humphreys BL, McCray AT. The unified medical language system. Methods Inform. Med. 1993;32:281–291
  11. Kors JA, Hoffmann AL. Induction of decision rules that fulfill user-specified performance requirements. Pattern Recognit. Lett. 1997;18:1187–1195
  12. Van der Lei J, Duisterhout JS, Westerhof H, Van der Does E, Cromme PVM, Boon WM, et al. The introduction of computer-based patient records in the Netherlands. Annu. Intern. Med. 1993;119:1036–1041
  13. Van der Lei J, Musen MA, van der Does E, Man in ’t Veld A, van Bemmel JH. Review of physician decision-making using data from computer-stored medical records. Lancet. 1991;338:1504–1508
  14. Van Wijk MA, van der Lei J, Mosseveld M, Bohnen AM, van Bemmel JH. Assessment of decision support for blood test ordering in primary care. A randomized trial. Ann. Intern. Med. 2001;134:274–281
  15. Van Bemmel JH, Kors JA, Van Herpen G. Methodology of the modular ECG analysis system MEANS. Methods Inform. Med. 1990;29:346–353
  16. Willems JL, Abreu-Lima C, Van Bemmel JH, et al. The diagnostic performance of computer programs for the interpretation of electrocardiograms. N. Engl. J. Med. 1991;325:1767–1773
  17. Kors JA, Crow RS, Hannan PJ, Rautaharju P, Folsom AR. Comparison of computer-assigned Minnesota codes with the visual standard method for new coronary heart disease events. Am. J. Epidemiol. 2000;151:790–797
  18. Vlug AE, Van der Lei J, Mosseveld BMT, Van Wijk MAM, Van der Linden PD, Sturkenboom MCJM, et al. Postmarketing surveillance based on electronic patient records: the IPCI project. Methods Inform. Med. 1999;38:339–344
  19. Visser LE, Vlug AE, Van der Lei J, Stricker BHC. Cough due to ACE inhibitors: a case-control study using automated general practice data. Eur. J. Clin. Pharmacol. 1996;49:439–444
  20. Van der Linden PD, Van der Lei J, Vlug AE, Stricker BHC. Skin reactions to antibacterial agents in general practice. J. Clin. Epidemiol. 1998;51:703–708
  21. Engelhart MJ, Geerlings MI, Ruitenberg A, et al. Dietary intake of oxidants and risks of Alzheimer's disease: the Rotterdam study. Am. J. Genet. 2002;70:1567–1574
  22. Gaspoz JM, Coxson PG, Goldman PA, Williams PA, et al. Cost-effectiveness of aspirin, clopidogrel, or both for secondary prevention of coronary heart disease. JAMA. 2002;287:3223–3229
  23. Hollander M, Bots ML, Iglesias der Sol A, et al. Cartotid plaques increase the risk of stroke and subtypes of cerebral infarction in asymptomatic elderly: the Rotterdam study. N. Engl. J. Med. 2002;346:1800–1806
  24. Vaessen N, Janssen JA, Heutink P, et al. Association between genetic variation in the gene for insulin-like growth factor-I. JAMA. 2002;288:2015–2022
  25. Njajou OT, Vaessen N, Joosse M, et al. A mutation in SLC11A3 gene is associated with autosomal dominant hemochromatosis. Nat. Genet. 2001;28:214–215
  26. Van Duijn CM, Dekker MCJ, Bonifati V, et al. PARK7, a novel locus for autosomal recessive early-onset Parkinsonism on chromosome 1p36. Am. J. Hum. Genet. 2001;69:629–634
  27. Bonifati V, Rizzu P, van Baren J, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism. Science. 2003;299:256–259

 This paper is the written version of an invited lecture given at the Plenary Session of the Conference EuroMISE 2004, in April 2004, at Charles University, Prague, Czech Republic. This conference was organized by the European Center for Medical Informatics, Statistics and Epidemiology (EuroMISE). Part of this paper was also presented in Brussels in September 2003 as a contribution to the deliberations on the European Research Area.

PII: S1386-5056(05)00153-X

doi: 10.1016/j.ijmedinf.2005.08.012

International Journal of Medical Informatics
Volume 75, Issue 3 , Pages 257-267 , March 2006